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V.A.C.® Therapy RCT Data Overview

Let the Data Speak for Itself

V.A.C. Therapy reduces time to healing by 16 days4

V.A.C. Therapy reduces time to wound healing
Median time to complete wound closure

Blume, et al. Comparison of Negative Pressure Wound Therapy (V.A.C. Therapy) to Advanced Moist Wound Therapy in the Treatment of Diabetic Foot Ulcers – a Multicenter Randomized Controlled Trial. Diabetes Care, 20084

  • 335 patients treated: V.A.C. Therapy, 169 patients; Advanced Moist Wound Therapy (AMWT), 166 patients. All data were calculated at end of 112-day active therapy phase

V.A.C. Therapy heals significantly more wounds2 (A greater proportion of foot ulcers achieved complete ulcer closure)

Higher proportion of healed wounds
Complete closure = 100% re-epithelialisation without drainage

Armstrong, et al. Negative Pressure Wound Therapy After Partial Diabetic Foot Amputation Negative. Lancet, 20052

  • 162 patients; V.A.C. Therapy, 77 patients; AMWT, 85 patients. All data were calculated at end of 112-day active therapy

V.A.C. Therapy lowers average total cost of treatment1

Lower average total cost of treatment for V.A.C. Therapy
Average total cost to achieve 100% healing ($)
Cost difference: $12,852

Apelqvist, et al. Resource Utilization and Economic Costs of Care Based on a Randomized Trial of Vacuum-Assisted Closure Therapy in the Treatment of Diabetic Foot Wounds. The American Journal of Surgery, 20081


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